I'd say so.
I've already talked about some plot ideas and themes, but geographically speaking Recife has some interesting stuff to it.
It's a big city cramped down by some other big cities. A tropical city cut by many rivers, Recife has 1,5 million souls living in it. It's a very culturally rich region filled with many movements unique to it. It has a very diverse set of locations with big buildings from where you can see the big skyline, the historical centre filled with buildings inspired by the portuguese/dutch time as a colony, little shanty towns near the rivers and the poor people in the suburbs in the hills.
photo
thanks skycrapercity
It might be too big for a HGW tho. Too much collateral damage