From the arcs I know of (even if I haven't seen them yet), events in Hinamizawa can take very different turns; there's one that's essentially a global zombie apocalypse, one that has Rika as a magical girl, and so forth. It doesn't seem a great stretch that you might eventually hit one where the background follows Nasuverse metaphysics - in which case, things like the dimensional looping (Second Magic), and the purported demon blood of the Three Great Families, can take on interesting implications . . .